Males accounted for almost 382,800 of the 696,962 deaths in the United States attributable to heart disease in 2020.  At 235.9 deaths per 100,000 population, heart disease was the leading cause of death among men in the United States in 2020, accounting for about 21.6% of all male deaths in the U.S. that year.  At the state level, there was a wide disparity in the rate of heart disease deaths among men.  In the ten states with the worst incidence of heart disease deaths for males, the death rate ranged from 23% to 42% higher than the male-only national average death rate from heart disease.  In comparison to the overall U.S. death rate from heart disease in 2020, these ten states had male death rates that ranged from 37% to 58% above the national average.  Further examination of data from the CDC's National Center for Health Statistics revealed the following details about the ten states with the highest male heart disease death rates in 2020:

Ten States with the Highest Male Heart Disease Death Rates

State/Deaths	Deaths	Population	Death Rate*
Alabama	7,951	2,376,966	334.5
Mississippi	4,786	1,435,815	333.3
Oklahoma	6,542	1,971,181	331.9
West Virginia	2,873	884,276	324.9
Arkansas	4,712	1,486,856	316.9
Louisiana	6,807	2,264,160	300.6
Michigan	14,678	4,907,813	299.1
Tennessee	9,945	3,358,020	296.2
Missouri	8,742	3,017,723	289.7
Kentucky	6,379	2,205,345	289.3
Total	73,415	23,908,155	307.1
U.S. Male Only	382,776	162,256,202	235.9
U.S. Female Only	314,186	167,227,921	187.9
U.S. Total	696,962	329,484,123	211.5

(*) number of heart disease deaths per 100,000 population

Source: CDC Wonder. Centers for Disease Control and Prevention, National Center for Health Statistics. Underlying Cause of Death 1999-2020 on CDC WONDER Online Database, released in 2021. Data are from the Multiple Cause of Death Files, 1999-2020, as compiled from data provided by the 57 vital statistics jurisdictions through the Vital Statistics Cooperative Program. Accessed on April 24, 2023

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Male Heart Disease Death Rates in the U.S. by Region