Of the nearly 697,000 heart disease deaths in the United States in 2020, 382,776 were men.  At 235.9 deaths per 100,000 population, the heart disease death rate for males in the U.S. in 2020 was about 25.5% higher than the female rate and  11.5% greater than the overall national heart disease death rate.  At the regional level, the male heart disease death rate was lowest in the five-state Rocky Mountain region and the highest in the five-state Great Lakes region.  A deeper dive into data from the National Center for Health Statistics details the following about male heart disease rates in the U.S. by region (follow the "region" links below for male heart disease death rate information at the state level within each region):

Male Heart Disease Death Rates in the U.S. by Region

Region	Deaths	Population	Death Rate*
Far West	54,932	28,192,091	194.8
Great Lakes	61,269	23,061,455	265.7
Great Plains	24,559	10,673,839	230.1
Mid-East	61,361	23,747,834	258.4
New England	15,387	7,242,931	212.4
Rocky Mountain	10,593	6,320,743	167.6
Southeast	109,168	41,736,692	261.6
Southwest	45,507	21,280,617	213.8
U.S. Male Only	382,776	162,256,202	235.9
U.S. Female Only	314,186	167,227,921	187.9
U.S. Total	696,962	329,484,123	211.5

(*) number of heart disease deaths per 100,000 population

Report Period: 2020

Source: CDC Wonder. Centers for Disease Control and Prevention, National Center for Health Statistics. Underlying Cause of Death 1999-2020 on CDC WONDER Online Database, released in 2021. Data are from the Multiple Cause of Death Files, 1999-2020, as compiled from data provided by the 57 vital statistics jurisdictions through the Vital Statistics Cooperative Program. Accessed on April 22, 2023