In 2020 there were over 96,000 drug-induced deaths in the United States or about 29.2 such deaths per 100,000 population.  By comparison, in 2019 the U.S. suffered just over 74,500 drug-induced deaths, recording 22.7 such deaths per 100,000 population.  The year-to-year increase in U.S. drug-induced deaths reflects the continuation of an unfavorable trend, that goes back at least two decades, in drug overdose deaths.  Since 1999, more than 93% of drug-induced deaths in the U.S. have been attributable to overdoses, both intentional and unintentional.  In 2020 the five-state Great Lakes region recorded nearly 15,900 drug-induced deaths, giving the region a collective drug-induced death rate of 33.9 such deaths per 100,000 population.  While the region's drug-induced death rate was 16% above the national average in 2020, these results were skewed by particularly high drug death rates in Ohio.  Two states in the region, Illinois and Wisconsin, recorded drug-induced death rates in 2020 that were below the national average.  A closer inspection of data from the National Center for Health Statistics reveals the following about drug-induced death rates in the Great Lakes region.:

Drug-Induced Death Rates in the Great Lakes Region

State	Deaths	Population	Death Rate*
Illinois	3,629	12,587,530	28.8
Indiana	2,369	6,754,953	35.1
Michigan	2,957	9,966,555	29.7
Ohio	5,376	11,693,217	46.0
Wisconsin	1,560	5,832,655	26.7
Region	15,891	46,834,910	33.9
U.S. Totals	96,096	329,484,123	29.2

(*) number of drug-induced deaths (intentional and unintentional) per 100,000 population

Report Period: 2020

Source: CDC Wonder. Centers for Disease Control and Prevention, National Center for Health Statistics. Underlying Cause of Death 1999-2020 on CDC WONDER Online Database, released in 2021. Data are from the Multiple Cause of Death Files, 1999-2020, as compiled from data provided by the 57 vital statistics jurisdictions through the Vital Statistics Cooperative Program. Accessed on October 8, 2022