In 2020, nearly 697,000 deaths in the United States were attributable to heart disease, about 5.8% more such deaths than in 2019.  The seven-state Great Plains region recorded nearly 45,100 heart disease deaths in 2020.  With 209.8 heart disease deaths per 100,000 population, the Great Plains' regional heart disease death rate was slightly better than the national average heart disease death rate of 211.5 per 100,000 population.  There was, however, wide disparity at the state level within the region, with Minnesota having one of the lowest state-level heart disease death rates in the country, while Missouri had one of the worst.  Further study of data from the CDC's National Center for Health Statistics yields the following state-level details about heart disease death rates in the Great Plains region:

Heart Disease Death Rates in the Great Plains Region

State	Deaths	Population	Death Rate*
Iowa	7,499	3,163,561	237.0
Kansas	6,264	2,913,805	215.0
Minnesota	8,562	5,657,342	151.3
Missouri	15,934	6,151,548	259.0
Nebraska	3,532	1,937,552	182.3
North Dakota	1,449	765,309	189.3
South Dakota	1,820	892,717	203.9
Region	45,060	21,481,834	209.8
U.S.	696,962	329,484,123	211.5

(*) number of heart disease deaths per 100,000 population

Report Period: 2020

Source: CDC Wonder. Centers for Disease Control and Prevention, National Center for Health Statistics. Underlying Cause of Death 1999-2020 on CDC WONDER Online Database, released in 2021. Data are from the Multiple Cause of Death Files, 1999-2020, as compiled from data provided by the 57 vital statistics jurisdictions through the Vital Statistics Cooperative Program. Accessed on June 22, 2022